When picking or editing a gaming or anime PFP, focus on a strong silhouette and...

https://remote-wiki.win/index.php/How_Do_Mobile_Games_Design_Characters_to_Stand_Out_on_Small_Screens%3F

When picking or editing a gaming or anime PFP, focus on a strong silhouette and make sure the face is cropped close to fill the circle. Keep backgrounds simple and avoid text so your icon stays clear even when tiny